Structural Biology Program
The Alexandros Pertsinidis Lab
Research
Alexandros Pertsinidis, PhD
Professor, Biochemistry and Structural Biology Program
Our mission is the development of a “new” generation of optical imaging technologies to enable advances in two hitherto difficult-to-investigate areas: the real-time analysis of macromolecular interactions and motions at the nanometer scale in vivo and the three-dimensional architecture of complex molecular machines and of subcellular ultrastructure, in situ. We are also refining and applying ultrahigh-resolution spectroscopy techniques to dissect multistep complex biochemical processes using in vitro reconstituted single-molecule assays.
Research Projects
Featured News
Going the Distance: How DNA Enhancers Communicate with Their Target Genes
Scientists at the Sloan Kettering Institute are learning how far-flung regions of genes connect to start the process of making proteins.
In the Lab
Scientists Develop a Tool to Watch a Single Gene Being Transcribed in a Living Cell
A new imaging technology developed at MSK allows researchers to focus on genes as they are copied into messenger RNA.
People
Alexandros Pertsinidis, PhD
Professor, Biochemistry and Structural Biology Program
- The Pertsinidis laboratory uses single-molecule approaches to understand gene transcription and the function of complex macromolecular machines inside live cells.
- PhD, Brown University
- PertsinA@mskcc.org
- Email Address
- 212-639-5258
- Office Phone
Members
Professor, Biochemistry and Structural Biology Program
Research Scholar
Research Fellow
Research Scholar
Research Fellow
Research Scholar
Research Associate
Research Fellow
Graduate Student
Graduate Student
Graduate Student
Research Technician
Undergraduate Student Intern
Masters Student Intern
Undergraduate Student Intern
Research Fellow
Administrative Research Assistant
Research Technician
Research Associate
Achievements
- Director’s New Innovator Award, National Institutes of Health (2012)
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