Immunology Program

The Joseph Sun Lab

Research

Pictured: Joseph Sun
Joseph Sun, PhD

The immune system responds to viral infections by introducing a complex interplay of immune cells and factors, whose goal is to eliminate the intruding pathogen. One such effector cell in the antiviral response is the Natural Killer (NK) cell, which secretes inflammatory cytokines and directly kills infected cells. The focus of our research is aimed at defining the signals that NK cells require to mount an effective immune response against pathogens. We are also exploring the regulatory mechanisms keeping NK cells in check, thereby safeguarding against potential autoimmunity.

View Lab Overview

The Sun Lab

Publications Highlights

Delconte RB, Owyong M, Santosa EK, Srpan K, Sheppard S, McGuire TJ, Abbasi A, Diaz-Salazar C, Chun J, Rogatsky I, Hsu KC, Jordan S, Merad M, Sun JC. 2024. Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity. Immunity. 57(8):1923-1938.e7.

Santosa EK, Kim H, Rückert T, Le Luduec JB, Abbasi AJ, Wingert CK, Peters L, Frost JN, Hsu KC, Romagnani C, Sun JC. 2023. Control of nutrient uptake by IRF4 orchestrates innate immune memory. Nat Immunol. 24(10):1685-1697.

View All Publications

People

Pictured: Joseph Sun

Joseph Sun, PhD

  • Immunologist Joseph Sun investigates the natural killer cell response against infection and cancer.
  • PhD, University of Washington
sunj@mskcc.org
Email Address
646-888-3228
Office Phone

Members

Veronica Shields
Administrative Assistant
Research Technician
Rebecca Delconte
Research Fellow
Graduate Student
Simon Grassmann
Research Fellow
GSK Student
Graduate Student
Graduate Student
Graduate Student
Adriana Mujal, PhD
Research Fellow
Mark Owyong
Graduate Student
Research Fellow
Research Technician
Jennifer Tsai
Clinical Fellow
Research Technician
Jenny M. Karo
Graduate Student; Current Position: Healthcare Investor- Counterpoint Global at Morgan Stanley, New York, NY
Sharline Madera
MD/PhD Student; Current Position: Resident, UCSF
Theresa L. Hunter (Geiger)
Graduate Student; Current Position: Principal Scientist, Capstan Therapeutics, Hayward, CA
Clair Geary
Graduate Student; Current Position: Science Policy Fellowship, National Academy of Sciences
Nicholas M. Adams
Tri-I MD-PhD Student; Current Position: Postdoctoral Fellow at NYU School of Medicine, New York, NY
Carlos Diaz Salazar Albelda
Graduate Student; Current Position: Postdoctoral Fellow at Columbia University, New York, NY
Endi Santosa
Graduate Student; Current Position: Postdoctoral Fellow at Genentech, San Francisco, CA
Aimee Beaulieu, Research Fellow
Research Fellow; Current Position: Assistant Professor, Rutgers Medical School
Matthew Firth, PhD
Research Fellow; Current Position: Research Scientist, Walter and Eliza Hall Institute
Timothy O'Sullivan
Research Fellow; Current Position: Assistant Professor, UCLA
Moritz Rapp
Research Fellow; Current Position: Research Scientist, Roche
Gabriela Wiedemann, PhD
Research Fellow; Current Position: Assistant Professor, Technical University of Munich
Colleen Lau
Research Fellow; Current Position: Assistant Professor, Cornell University
Jessica Sharrock, PhD
Research Fellow; Current Position: Scientific Consulting
Sam Sheppard
Research Fellow; Current Position: Lecturer, Imperial College London
Carolyn Zawislak
Research Technician; Current Position: Residency, MD Anderson
Lex Johnson
Research Technician; Current Position: Graduate Student, U Penn
Orrel Weizman
Research Technician; Current Position: Graduate Student, Yale
Cindy Zhang
Research Technician; Current: Biotech company
Ella Schochet
Research Technician; Current Position: Graduate Student, Weill Cornell
Aamna Abbasi
Research Technician; Current Position: Graduate Student, Duke
Claire Wingert
Research Technician; Current Position: Graduate Student, Weill Cornell
2012 SURP Student; Current Position: Graduate school, Ohio State University
2019 SURP student; Current Position: MD-PhD student, University of North Carolina
Student Researcher; Current Position: Medical School, Columbia University College of Physicians and Surgeons
Christopher Irwin
Student Researcher; Current Position: Medical Student, Rutgers Medical School
Kai Yee
Student Researcher; Current Position: Medical School, UC Davis
Celeste Dang
Graduate Student; Current Position: Research Associate - Immunology, Memorial Sloan Kettering Cancer Center

Achievements

  • Weill Cornell Graduate School Outstanding Teaching & Mentoring Award (2022)
  • American Cancer Society Research Scholar (2017)
  • Burroughs Wellcome Fund Investigator in Infectious Disease (2016)
  • Boyer Young Investigator Award for Basic Research (2015)
  • Geoffrey Beene Junior Faculty Chair (2014)
  • AAI Pfizer-Showell Early Career Investigator Award (2012)
  • Searle Scholar Award (2011)
  • Cancer Research Institute Investigator Award (2011)

Lab News & Events

Upcoming event

Regulation of Dendritic Cell-mediated Peripheral Tolerance

Memorial Sloan Kettering Cancer Center
Zuckerman Research Center
417 East 68th Street
Room ZRC-Auditorium
New York, NY 10065

Lab Photo Album

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs

Career Opportunities

Apply now

Get in Touch

Disclosures

Members of the MSK Community often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community. These activities outside of MSK further our mission, provide productive collaborations, and promote the practical application of scientific discoveries.

MSK requires doctors, faculty members, and leaders to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public. Not all disclosed interests and relationships present conflicts of interest. MSK reviews all disclosed interests and relationships to assess whether a conflict of interest exists and whether formal COI management is needed.

Joseph Sun discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2024 through disclosure submission in spring 2025). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


View all disclosures