Immunology Program

The Jayanta Chaudhuri Lab

Research

Pictured: Jayanta Chaudhuri
Jayanta Chaudhuri, PhD

Laboratory of Molecular and Cellular Immunology

Recombination, genomic integrity, and heterogeneity in B cells
 

scientific diagram

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The Jayanta Chaudhuri Lab (2023)
The Jayanta Chaudhuri Lab (2018)

Featured News

In the Lab
Kalina Belcheva, Teddy Yewdell, Jayanta Chaudhuri, and Ryan Smolkin standing together in a lab
SKI Research Reveals New Insights into Immune Response to Viral Infections — Including COVID-19
Research from Sloan Kettering Institute immunologists suggests that the body may mount an immune response to respiratory viruses that lasts longer than previously thought. The discovery could impact the timing of COVID-19 vaccinations.
Jayanta Chaudhuri
At Work: Immunologist Jayanta Chaudhuri
Immunologist Jayanta Chaudhuri has long been interested in biology, Mendelian genetics, and the story of how life evolved.
In the Community
Allysia Matthews, with Citymeals-on-Wheels staff donating reusable ice packs
Giving Supplies a Second Life, and Making an Environmental Impact in the Process
Memorial Sloan Kettering “green” committees focus on waste reduction and energy efficiency throughout the institution while donating useful supplies to New York–area nonprofits.

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Publications Highlights

Sharma, R., Smolkin, R. M., Chowdhury, P., Fernandez, K. C., Kim, Y., Cols, M., Alread, W., Yen, W.-F., Hu, W., Wang, Z.-M., Violante, S., Chaligné, R., Li, M. O., Cross, J. R., & Chaudhuri, J. (2023). Distinct metabolic requirements regulate B cell activation and germinal center responses. Nature Immunology, 24(8), 1358–1369. https://doi.org/10.1038/s41590-023-01540-y

Fernandez, K. C., Feeney, L., Smolkin, R. M., Yen, W.-F., Matthews, A. J., Alread, W., Petrini, J. H. J., & Chaudhuri, J. (2022). The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes. eLife, 11, e77073. https://doi.org/10.7554/eLife.77073

Maekawa, K., Yamada, S., Sharma, R., Chaudhuri, J., & Keeney, S. (2022). Triple-helix potential of the mouse genome. Proceedings of the National Academy of Sciences of the United States of America, 119(19), e2203967119. https://doi.org/10.1073/pnas.2203967119

Yewdell, W. T., Smolkin, R. M., Belcheva, K. T., Mendoza, A., Michaels, A. J., Cols, M., Angeletti, D., Yewdell, J. W., & Chaudhuri, J. (2021). Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports, 37(6), 109961. https://doi.org/10.1016/j.celrep.2021.109961

Mendoza, A., Yewdell, W. T., Hoyos, B., Schizas, M., Bou-Puerto, R., Michaels, A. J., Brown, C. C., Chaudhuri, J., & Rudensky, A. Y. (2021). Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Science Immunology, 6(60), eabi4710. https://doi.org/10.1126/sciimmunol.abi4710

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People

Pictured: Jayanta Chaudhuri

Jayanta Chaudhuri, PhD

  • Immunologist Jayanta Chaudhuri studies the mechanisms of immunoglobulin gene diversification.
  • PhD, Albert Einstein College of Medicine
chaudhuj@mskcc.org
Email Address
646-888-2357
Office Phone

Members

Jayanta Chaudhuri, PhD
Jayanta Chaudhuri
Principal Investigator
Stephanie Downs-Canner
Stephanie Downs-Canner
Assistant Attending Surgeon
Memorial Sloan Kettering Medical Oncologist Jennifer Lue
Jennifer Lue
Assistant Attending
Francesca Manara
Francesca Manara
Postdoctoral Research Fellow
Laura Nicolas Gomariz, PhD
Laura Nicolas Gomariz
Postdoctoral Research Fellow
Maria Maddalena Perra
Postdoctoral Research Fellow
Keith Fernandez
Keith Fernandez
Graduate Student
Ryan Smolkin
Ryan Smolkin
Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center
Kalina Belcheva
Kalina Belcheva
Graduate Student
Vivian Kuan
Vivian Kuan
Graduate Student
Kanelly Reyes
Kanelly Reyes
Research Technician
Matthew Kantorski
Research Technician
Lorraine Hernandez Delgado
MSK Bridge Scholar
Veronica Shields
Veronica Shields
Administrative Assistant
Youngjun Kim
Youngjun Kim
Graduate Student
Marisa Lazarus
Marisa Lazarus
Research Technician
Rahul Sharma
Rahul Sharma
Postdoctoral Research Fellow
William Alread
William Alread
Research Technician
Priyanka Chowdhury
Priyanka Chowdhury
Graduate Student
William Yewdell
William T. Yewdell
Postdoctoral Research Fellow
Silva Baburyan
Silva Baburyan
Research Technician
Zahra Hudda
Pediatric Hematology-Oncology Fellow
Montserrat Cols Vidal
Montserrat Cols Vidal
Lab Manager
Wei-Feng Yen
Wei-Feng Yen
Graduate Student
Joseph N. Pucella
Joseph N. Pucella
Faculty Research Instructor, NYU School of Medicine, NYU Langone Medical Center
William Terry
Pediatric Hematology-Oncology Fellow
Kayleigh-Herrick Reynolds
Kayleigh-Herrick Reynolds
Research Technician
Bharat Vaidyanathan
Bharat Vaidyanathan
Graduate Student
Lauren J. Dimenna
Lauren J. Dimenna
Graduate Student
Simin Zheng
Simin Zheng
Graduate Student
Bao Q. Vuong
Postdoctoral Research Fellow
Allysia Matthews
Allysia Matthews
Graduate Student
Urszula Nowak
Graduate Student

Open Positions

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Disclosures

Members of the MSK Community often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community. These activities outside of MSK further our mission, provide productive collaborations, and promote the practical application of scientific discoveries.

MSK requires doctors, faculty members, and leaders to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public. Not all disclosed interests and relationships present conflicts of interest. MSK reviews all disclosed interests and relationships to assess whether a conflict of interest exists and whether formal COI management is needed.

Jayanta Chaudhuri discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2024 through disclosure submission in spring 2025). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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