Cell Biology Program
The Michael Overholtzer Lab
Research
The Overholtzer lab studies mechanisms of nutrient sensing and cellular responses to nutrient starvation, including the nutrient recycling pathway autophagy, scavenging pathways such as macropinocytosis, and mechanisms of cell death. We investigate cell death mechanisms that have unique effects on cell populations, including entosis that supports the survival of starved cells and promotes cell competition, and ferroptosis that eliminates starved cell populations by propagating from cell to cell. The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis.
Research Projects
Overholtzer Lab
Featured News
People
Michael Overholtzer, PhD
Dean, Gerstner Sloan Kettering Graduate School
- Cell biologist Michael Overholtzer studies the mechanisms of tumor initiation and progression, cell adhesion, and cell death.
- PhD, Princeton University
- overhom1@mskcc.org
- Email Address
- 212-639-6536
- Office Phone
Members
Administrative Assistant, Sr.
Research Scholar
Graduate Student, WCMC
GSK Graduate Student
Graduate Student, WCMC
Research Scholar
GSK Graduate Student
Lab Alumni
Lab Head at Babraham Institute
Associate Investigator at Institute of Biotechnology, China
Associate Professor at Korea University, South Korea
Manager/Process Expert at Lonza in Visp, Switzerland
Staff Scientist at Salk Institute for Biological Sciences, La-jolla, California
Research Associate
Graduate Student
Senior Scientist at Boehringer Ingelheim Pharmaceuticals, Inc.
Research Fellow
Graduate Student
Research Associate
Graduate Student
Technical Regulatory Affairs Manager at Roche in Basel, Switzerland
