Cell Biology Program
The Xuejun Jiang Lab
Research
Xuejun Jiang, PhD
Virginia and Daniel K. Ludwig Chair
The research of my laboratory focuses on two directions highly relevant to cancer biology, (1) the molecular basis of programmed cell death processes (including apoptosis and ferroptosis), and their roles in human disease; and (2) the molecular basis of autophagy and its role in cancer. We also study various cancer signaling and cellular metabolic events, especially those involved in cell death/survival determination. We aim to translate our basic research finding into potential therapeutic approaches. To achieve these goals, the laboratory utilizes a combination of approaches including biochemistry, chemical biology, proteomics, molecular cell biology, high-throughput screening, 3-dimensional microfluidic cell array, and mouse modeling.
Featured News
MSK Research Highlights, June 29, 2023
New MSK research discovered ferroptosis regulators that suggest therapeutic opportunities against hormone receptor-positive cancers; examined how tumor-associated macrophages might be turned against cancer; acquired new insights into joint inflammation in rheumatoid arthritis; developed a systems-level platform called epichaperomics to map changes in interactors among thousands of proteins involved in cancer-related processes; and investigated how artificial intelligence could help diagnose an invasive form of breast cancer.
In the Lab
More Evidence that Cellular ‘Death by Iron’ Could Be Promising Avenue of Cancer Treatment
Cancers with certain mutations are vulnerable to ferroptosis, a form of iron-dependent cell death.
Finding
Scientists See Potential in Cellular 'Death by Iron' for Cancer Treatment
This form of cell death is called ferroptosis, and certain cancer cells are especially vulnerable to it.
People
Xuejun Jiang, PhD
Virginia and Daniel K. Ludwig Chair
- Cell biologist Xuejun Jiang studies programmed cell death, molecular mechanisms, and their roles in tumorigenesis.
- PhD, University of Texas Southwestern Medical Center at Dallas
- jiangx@mskcc.org
- Email Address
- 212-639-6814
- Office Phone
Members
Research Fellow
Graduate Student, Tri-I PhD Program in Chemical Biology
Graduate Student, GSK
Project Coordinator
Graduate Student, GSK
Graduate Student, Tri-I PhD Program in Chemical Biology
Graduate Student, WCM
Lab Head
Research Fellow
Research Scholar
Graduate Student, Tri-I PhD Program in Chemical Biology
Senior Research Scientist
Research Scholar
University Assistant at Johannes Kepler University
Scientist, International Flavors & Fragrances
Principal Scientist, Accutar Therapeutics
Group Leader - Reader, The University of Edinburgh
Programme Leader at MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee
Principal Investigator and Professor, Harbin Institute of Technology
Associate Professor, Department of Biochemistry and Molecular Biology, Penn State Cancer Institute
Research Scientist, MSKCC
Postdoc Research Fellow at Ben Gurion University of the Negev, Israel
Manager of Regulatory Affairs Strategy, Regeneron Pharmaceuticals, Inc.
Assistant Investigator, Chinese Institutes for Medical Research Beijing
Scientist, Lime Therapeutics
Principal Scientist at Wave Life Sciences, Boston, MA
Freelance, Medical Communications Consultant
President and Founder of Bon Opus Biosciences
R&D Director, HydroGene Therapeutics
Vice Director at Zhangjiagang Hospital
Drug Discovery Scientist, Bristol Myers Squibb
Principal Investigator, Peking University International Cancer Center
Principal Investigator at Roswell Park Cancer Institute
Graduate Student, SUNY Downstate Health Sciences University
Innovative Cell biology Researcher at National Singapore University
Professor at Fourth Military Medical University, Xi'an
Program Manager at Center Ministry of Science and Technology, China
Professor at Air Force Military Medical University, China
Graduate Student, WCMC
Exchange Graduate Student
Achievements
- Louis and Allston Boyer Young Investigator Award for Basic Research, Memorial Sloan Kettering Cancer Center (2007)
- Scholar, American Cancer Society (2007-2010)
- Catherine and Frederick Adler Chair for junior faculty, Memorial Sloan Kettering Cancer Center (2006)
- V Scholar, The V Foundation for Cancer Research (2004-2006 )
- Alfred Bressler Scholar, Alref W. Bresller Scholars Fund (2004-2007)
- Sigma Xi Award, UT Southwestern (1998)
- Robert A. Welch Predoctoral Fellowship, UT Southwestern (1995-1999)