Choosing Ovarian Preservation or Removal before Surgery for Endometrial Cancer

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Full Title

Preservation of Ovaries in Endometrial Malignancies: GYN POEM Trial

Purpose

The purpose of this study is to learn how cancer-related distress and/or reproductive concerns affect a woman’s decision to remove or preserve her ovaries during surgery for endometrial cancer. Participants in this study will include premenopausal woman with endometrial cancer who will be having surgery to treat the cancer. Before the surgery, they will decide whether to preserve their ovaries or have them removed. Preserving the ovaries will allow them to harvest their eggs after surgery and help manage their hormone levels.

Researchers will also assess ovarian reserve in participants who choose to preserve their ovaries. All participants will be monitored for recurrence of cancer after surgery according to the standard of care, including physical examinations, biopsy procedures (if needed), and imaging scans (if needed).

Who Can Join

Participants in this study will include women ages 18-50 having surgery for stage I endometrial cancer.

For more information about this study, please contact Gabrielle Bennetti via email at bennetg1@mskcc.org.

Protocol

20-429

Disease Status

Newly Diagnosed & Relapsed/Refractory

Investigator

Co-Investigators

ClinicalTrials.gov ID

NCT04569773