Full Title
A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Haploidentical Related, Partially HLA-Mismatched, or Matched Unrelated Bone Marrow for Newly Diagnosed Patients with Severe Aplastic Anemia [NMDP IRB] (BMT CTN)Purpose
Severe aplastic anemia is a serious condition where the bone marrow does not make the normal amount of blood cells. Bone marrow transplantation is one way to treat this disease. It has been reserved for people under age 40 with a related donor whose cells fully match theirs. However, advances have been made in bone marrow transplantation that make it an option for more people.
This study is assessing different kinds of bone marrow transplantation for children and adults with severe aplastic anemia. The people in this study have aplastic anemia that has not yet been treated. They include:
- People who do not have a related fully matched bone marrow donor.
- People with a half-matched donor.
- People with an unrelated donor who is a full or partial match.
Who Can Join
To join this study, there are a few conditions. You or your child must:
- Have severe aplastic anemia that has not yet been treated.
- Not have a fully matched related bone marrow donor.
- Be age 3 to 75 years old.
Contact
For more information and to see if you or your child can join this study, please call Dr. Brian Shaffer’s office at 646-608-3737.