A Phase 3 Study of Reduced Dose Radiation Therapy for People With B-Cell Lymphoma

Full Title

A Prospective Phase III Study Comparing Standard Radiotherapy (24 Gy) with a PET REsponse-guided Very Low Dose (4 Gy) Staged Radiotherapy Strategy for Potentially Curable, Indolent B-cell Lymphomas

Purpose

Researchers want to see if a lower dose of radiation therapy works as well as the standard dose in people with lymphoma. The people in this study have B-cell lymphoma that has not yet been treated.

If you take part in this study, you will be randomly assigned to get either:

  • Very low-dose radiation therapy.
  • Standard radiation therapy.

Who Can Join

To join this study, there are a few conditions. You must

  • Have stage 1 or 2 follicular lymphoma or marginal zone lymphoma that has not yet been treated.
  • Be age 18 or older.

Contact

For more information and to see if you can join this study, please call Dr. Brandon Imber’s office at 631-212-6346.

Protocol

25-089

Phase

Phase III (phase 3)

Disease Status

Relapsed or Refractory

Investigator

Co-Investigators

ClinicalTrials.gov ID

NCT07029217