Anaeze Offodile II, MD, MPH

Chief Strategy Officer
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Anaeze Offodile II, MD, MPH

Dr. Anaeze Offodile is a dynamic healthcare executive, surgeon, and global  thought leader who serves as Chief Strategy Officer at Memorial Sloan Kettering Cancer Center (MSK). In this role, he leads MSK’s enterprise growth agenda, drives high-impact innovation and commercialization efforts, and spearheads strategic planning across the institution. At the forefront of MSK’s transformation, Dr. Offodile is the architect of major initiatives that aim to redefine the organization and provision of cancer care through technological advancement, value-based delivery, and translational science.

Widely regarded as MSK’s “futurist,” Dr. Offodile translates macro-level trends in emerging technologies, healthcare delivery, and scientific discovery into actionable institutional strategies. He leads cross-functional teams that incubate new business ventures, deploy advanced analytics and AI capabilities, structure industry partnerships, and support enterprise-wide decision-making—all with the goal of enhancing patient outcomes, operational agility, and financial sustainability.

His recent accomplishments include launching MSK’s first-ever integrated strategic plan (“MSK 2030”), a strategic affiliation program that extends MSK’s expertise, protocols and brand to health systems across the US (“Care Partners”) and  a startup incubator (“Entrepreneurship Initiative”);  expanding the functionality of MSK Innovation Hub (iHub); creating the AI-focused Technology Development Fund (aiTDF); and overseeing the formation of the MSK Therapeutics Accelerator. He was the principal architect of MSK’s strategic collaboration with Amazon Web Services (AWS) to scale the institution’s data and cloud infrastructure and catalyze digital transformation.

Previously, Dr. Offodile was Enterprise Executive Director for Clinical Transformation at the University of Texas MD Anderson Cancer Center, where he launched several first-in-oncology care delivery models to provide high-acuity services in the home and community. Clinically trained as a plastic and reconstructive surgeon, he maintained an active surgical practice focused on complex oncologic reconstruction.

A widely recognized authority on health policy and systems innovation, Dr. Offodile has served as Special Advisor to the President of the National Academy of Medicine and Policy Advisor to the Center for Medicare and Medicaid Innovation. He was previously a Nonresident Scholar in Health Policy at the Baker Institute for Public Policy at Rice University and the 2019–2021 Gilbert S. Omenn Fellow at the National Academy of Medicine. An accomplished health policy researcher with active R37 NCI funding, he also serves on the Editorial Board of Annals of Surgery

Born in London, Dr. Offodile holds a BS from Kent State, an MD from Columbia University, and an MPH from Johns Hopkins. He completed his surgical training at Brigham and Women’s Hospital, Lahey Hospital and Medical Center, and MD Anderson Cancer Center. His clinical practice is centered around abdominal wall and breast reconstruction.