Proteomics
Overview
The Proteomics Core provides mass spectrometric sequencing and quantitation of peptides and proteins to support basic, translational, and clinical research programs at MSK. The Core utilizes modern high-resolution mass spectrometry and nanoscale liquid chromatography in conjuction with biochemical processing of samples with the end goal of determining the identity, relative abundance, and presence of post translational modifications from purified components, cell lysates, tissues, and select fluid such as cerebral spinal fluid. Proteins and post translational modification are critical components of complex signaling pathways underlying development, cell growth, differentiation, DNA repair, senescence, immune response to cancer, and response to bioactive therapies. Dissection of these pathways can lead to insights on the underlying molecular mechanisms involved in cancer. The Proteomics Core seeks to be an efficient, user friendly, state-of-the-art facility. Advice is provided by the Core staff to facilitate the design, execution, and analysis of experiments. Over the past year, the Core has supported research from 38 investigators.
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Director
Members
Senior Research Specialist
Research Technician
Bioinformatics Engineer
SKI Administrative Assistant II
Research Assistant
Research Technician
Research Technician
Alumni
Research Technician
Research Assistant
Senior Application Analyst
Research Technician
Senior Research Technician
Senior Research Scientist
Research Technician
Senior Research Technician
Research Assistant
Administrative Assistant II
Senior Research Scientist
