Description

This is a collection of renal cell carcinoma (RCC) cell lines derived from the primary tumors of patients who underwent surgery.

Primary Human Renal Cell Carcinoma (RCC) Cell Line Collection

* A cell line established from a metastatic site in the same patient is available. Please contact us for more details.

Adapted from Ebert T et al. Cancer Research 50: 5531-5536 (1990)

Source

All cell lines were established in Dr. Lloyd Old’s laboratory, from patients undergoing nephrectomy at Memorial Hospital, Memorial Sloan Kettering Cancer Center, between the years 1972 and 1987. Fresh surgical specimens were obtained from Tumor Procurement Services, Department of Surgical Pathology, Memorial Hospital, Memorial Sloan Kettering

Inventors

Lloyd J. Old, MD, former William E. Snee Chair in Cancer Immunology, Memorial Sloan Kettering; former Director, New York Branch, Ludwig Institute for Cancer Research, and members of the Old Laboratory

Key References

• Ueda R et al. (1979) Cell surface antigens of human renal cancer defined by autologous typing. Journal of Experimental Medicine 150: 564-579 (PubMed ID: 479762)
• Ebert T et al. (1990) Establishment and characterization of human renal cancer and normal kidney cell lines. Cancer Research 50: 5531-5536 (PubMed ID: 2386958)
• Sjölund J et al. (2008) Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo. Journal of Clinical Investigation 118: 217-228 (PubMed ID: 18079963)

Licensing Information

These cell lines may be nonexclusively licensed, individually or in any preferred combination, for research or commercial purposes.

Contact Information