Cell-free DNA ChIP

Cell-free DNA ChIP

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More about cell-free DNA ChIP

  • A modified ChIP approach designed to profile chromatin modifications from circulating cell-free DNA (cfDNA). This method enables the study of epigenetic marks in plasma and other biofluids, providing insights into gene regulation, cancer epigenetics, and liquid biopsy applications.

Reference: Sadeh. et al., ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells of origin. Nature Biotech, 2021. 39(5):586-598