Baako AK, Vijayakumar R, Medina-Cano D, Wang Z, Romero Pichardo J, Fadojutimi K, Do S.C, Lin Y, Islam MT, Dixit S, Trzeciak A, Perry JSA#, Vierbuchen T# (2025) Modelling tissue-resident macrophage development from mouse pluripotent stem cells. bioRxiv (doi: https://doi.org/10.1101/2025.05.01.651743)
Ee LS*, Medina-Cano D*, Goetzler E, Uyehara CM, Schwarz C, Salataj E, Madhuranath S, Evans T, Hadjantonakis AK, Apostolou E, Polyzos A, Vierbuchen T#, Stadtfeld M# (2025). Enhancer remodeling by Otx2 directs specification and patterning of mammalian definitive endoderm (accepted in principle, Developmental Cell)
Medina-Cano D*, Islam MT*, Petrova V*, Dixit S, Balic Z, Yang MG, Stadtfeld M, Wong ES#, Vierbuchen T#. (2024) A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro. bioRxiv (doi: https://doi.org/10.1101/2024.09.30.615887) (accepted, Developmental Cell)
Glenn RA, Do SC, Guruvayurappan K, Corrigan EK, Santini L, Medina-Cano D, Singer S, Cho H, Liu J, Broman K, Czechanski A, Reinholdt L, Koche R, Furuta Y, Kunz M, Vierbuchen T (2024). A pluripotent stem cell platform for in vitro systems genetics studies of mouse development. bioRxiv doi: 10.1101/2024.06.06.597758
Parikh C.*, Glenn R.*, Shi Y.*, Chatterjee K., Swanzey E., Singer S., Do S.C., Zhan Y., Furuta Y., Tahiliani M., Apostolou E., Polyzos A., Koche R., Mezey J.#, Vierbuchen T.#, Stadtfeld M.# (2024) Genetic variation modulates susceptibility to aberrant DNA hypomethylation and imprint deregulation in naive pluripotent stem cells. Stem Cell Reports (20), Issue 4, 102450 doi: https://doi.org/10.1016/j.stemcr.2025.102450
Petrova V, Niu M, Vierbuchen T, Wong ES (2025). Studying cis-regulatory heterogeneity in single-cells at allelic resolution. bioRxiv doi: https://doi.org/10.1101/2025.04.16.649227
Adli M, Przybyla L, Burdett T, Burridge PW, Cacheiro P, Chang HY, Engreitz JM, Gilbert LA, Greenleaf WJ, Hsu L, Huangfu D, Hung LH, Kundaje A, Li S, Parkinson H, Qiu X, Robson P, Schürer SC, Shojaie A, Skarnes WC, Smedley D, Studer L, Sun W, Vidović D, Vierbuchen T, White BS, Yeung KY, Yue F, Zhou T; MorPhiC Consortium. MorPhiC Consortium: towards functional characterization of all human genes. Nature. 2025 Feb;638(8050):351-359. doi: 10.1038/s41586-024-08243-w
Medina-Cano D*, Corrigan EK*, Glenn RA, Islam MT, Lin Y, Kim J, Cho H, Vierbuchen T (2022) Rapid and robust directed differentiation of mouse epiblast stem cells into definive endoderm and forebrain organoids. Development doi: 10.1242/dev.200561
Yang MG*, Ling E*, Cowley CJ, Greenberg ME#, Vierbuchen T# (2022) Characterization of sequence determinants of enhancer function using natural genetic variation. eLife doi: 10.7554/eLife.76500
Renthal W*, Boxer LD*, Hrvatin S, Li E, Silberfeld A, Nagy MA, Griffith EC, Vierbuchen T, Greenberg ME. Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing. Nature Neuroscience doi: 10.1038/s41593-018-0270-6
Vierbuchen T*, Ling E*, Cowley C, Couch C, Harmin DA, Wang X, Roberts CW, Greenberg ME. AP-1 transcription factors and the BAF complex mediate signal-dependent enhancer selection. Molecular Cell 68, 1067-1082 (2017) doi: 10.1016/j.molcel.2017.11.026
Mall M, Kareta M, Chanda S, Ahlenius H, Perotti N, Greider S, Ge X, Drake S, Ang CE, Vierbuchen T, Fuentes D et al. Myt1l safeguards neuronal identity by actively repressing non-neuronal fates. Nature 544, 245-249 (2017) doi: 10.1038/nature21722
Malik AN*, Vierbuchen T*, Hemberg M, Rubin AA, Ling E, Couch CH, Stroud H, Spiegel I, Farh KK, Harmin DA, Greenberg ME. Genome-wide identification and characterization of functional neuronal activity-dependent enhancers. Nature Neuroscience 10, 1330-39 (2014) doi: 10.1038/nn.3808
Wapinski OL*, Vierbuchen T*, Qu K, Lee QY, Chanda S, Fuentes D, et al. Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons. Cell 155(3), 621-35 (2013) doi: 10.1016/j.cell.2013.09.028
Webb AE, Pollina E, Vierbuchen T, Ucar D, Avellaneda NU, Martynoga B, Sewak M, Wernig M, Guillemot F, Brunet A. FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Reports 4(3), 477-91 (2013) doi: 10.1016/j.celrep.2013.06.035
Yang N, Zuchero JB, Ahnlenius H, Marro S, Ng YH, Vierbuchen T, Barres BA, Wernig M. Generation of oligodendroglial cells by direct lineage conversion. Nature Biotechnology 31, 434-439 (2013) doi: 10.1038/nbt.2564
Vierbuchen T, M Wernig. Molecular roadblocks for cellular reprogramming. Molecular Cell 47, 827-838 (2012) doi: 10.1016/j.molcel.2012.09.008
Vierbuchen T, M Wernig. Direct Lineage Conversions: Unnatural but useful? Nature Biotechnology 29, 892-907 (2011) doi: 10.1038/nbt.1946
Pang ZP*, Yang N*, Vierbuchen T* et al. Induction of human neuronal cells by defined transcription factors. Nature 476, 220-223 (2011) doi: 10.1038/nature10202
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof T, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035–1041 (2010) doi: 10.1038/nature08797