David B. Solit

Pictured: David Solit -- Geoffrey Beene Chair; Director, Center for Molecular Oncology

Areas of Expertise

Conditions I Treat

Prostate cancer and conditions
Genitourinary cancers and conditions
Bladder cancer

My Specialties

Chemotherapy
Targeted therapy
Immunotherapy

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Get to Know Me

I am a medical oncologist and a laboratory scientist. As a member of the Genitourinary Oncology Service, I specialize in treating cancers of the prostate, bladder, kidney, testis, and other related cancers.

This provider is part of a team that was ranked #1 in the nation for Urology Cancer Care this year by U.S. News & World Report.

I treat my patients with chemotherapy, targeted therapies, immunotherapy, or combinations of these drugs. At Memorial Sloan Kettering Cancer Center (MSK), I work with other cancer experts, including surgeons and radiation oncologists, to develop an individual treatment plan for each patient.

I am very involved in clinical trials, particularly those of targeted drugs known as kinase inhibitors, which block pathways inside cancer cells that cause the cells to grow or spread. One area of focus in my research is studying patients who are known as extraordinary responders. These are people with difficult-to-treat cancers who are found to respond exceptionally well to a new drug, even though that drug does not work in most people with the same disease.

My laboratory in the Human Oncology and Pathogenesis Program at Memorial Sloan Kettering completed the first whole-genome analysis of a patient with bladder cancer. This patient had a complete and durable response to a novel targeted drug that was effective in only a small minority of patients. By performing this analysis, we were able to determine what was genetically unique about this patient’s tumor. We are now testing the same drug in other patients whose tumors have a similar genetic profile.

As the Director of the Marie-Josée and Henry R. Kravis Center for Molecular Oncology (CMO) at MSK, I also lead a multidisciplinary team of clinicians, geneticists, bioinformaticians, and laboratory scientists. The mission of the CMO is to integrate molecular and clinical information to develop therapies that are individualized to each patient’s cancer.

My colleagues and I work to make sure that all patients who come to MSK receive the best care possible, whether that means conventional or experimental therapies.

What I Do at MSK

I'm a genitourinary (GU) medical oncologist, which is a cancer doctor who specializes in genitourinary (jeh-nih-toh-YOOR-ih-nayr-ee) cancers. This includes bladder, kidney, penis, prostate, and testicular cancers.

Geoffrey Beene Chair
Director, Marie-Josée and Henry R. Kravis Center for Molecular Oncology

Conditions I Treat

Prostate cancer and conditions
Genitourinary cancers and conditions
Bladder cancer
Kidney (renal cell) cancer and conditions
Testicular cancer

My Specialties

Chemotherapy
Targeted therapy
Immunotherapy
Combination therapy
Clinical trials

Education

MD, University of Pennsylvania School of Medicine

Residencies

Internal Medicine - Barnes Jewish Hospital

Fellowships

Medical Oncology/Hematology - Memorial Sloan Kettering Cancer Center
Medicine - Weill Cornell Medical College

Board Certifications

Internal Medicine
Medical Oncology

Insurance Information

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If you have questions about insurance, call us at 646-497-9176.

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New Patients

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Current Patients

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Contact and Location

Office Phone

646-888-5435

Location

New York, NY

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Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

See all Genitourinary Oncology Service doctors

Clinical Trials

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Search clinical trials

Research and Publications

View Dr. Solit's Lab

Publications on PubMed

Visit PubMed for a full listing of Dr. Solit’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.

See all on PubMed

Disclosures

Members of the MSK Community often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community. These activities outside of MSK further our mission, provide productive collaborations, and promote the practical application of scientific discoveries.

MSK requires doctors, faculty members, and leaders to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public. Not all disclosed interests and relationships present conflicts of interest. MSK reviews all disclosed interests and relationships to assess whether a conflict of interest exists and whether formal COI management is needed.

David B. Solit discloses the following relationships and financial interests:

Antares Therapeutics, Inc.
Equity
BridgeBio Inc.
Professional Services and Activities
Corramedical, Inc.
Equity
Elsie Biotechnologies, Inc.
Equity; Professional Services and Activities
Fog Pharmaceuticals, Inc.
Professional Services and Activities
Fore Biotherapeutics
Equity; Professional Services and Activities

Function Oncology, Inc.
Equity; Professional Services and Activities
Meliora Therapeutics
Professional Services and Activities
Paige.AI, Inc.
Professional Services and Activities
Pfizer, Inc.
Professional Services and Activities
Pyramid Biosciences, Inc.
Equity; Professional Services and Activities
Scorpion Therapeutics, Inc.
Equity; Professional Services and Activities

If you’re a patient at MSK and would like more information about your doctor’s external relationships, please talk with your doctor.

The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2024 through disclosure submission in spring 2025). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.

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